As essential as it is to know the pathophysiology of various diseases and the pharmacological and surgical interventions used to treat them, it is also necessary to understand the social and psychological aspects of illness in order to effectively treat patients. Physicians must situate their treatments within psychosocial parameters that best serve the individual patient, asking questions like, “What will motivate this patient to take his medication as prescribed?” and “How do the social supports of this single parent influence his or her ability to get his/her child to well-visits with the pediatrician?”