We all know medical school interviews are important. But did you know, according to a survey of medical school admissions committees conducted by the American Association of Medical Colleges (AAMC), interviews are the most important factor used to decide which applicants gain acceptance (Dunleavy DM, et al. Medical School Admissions: More than Grades and Test Scores. AIB. 11 (6), 2011)? The most important factor! Fortunately, interview techniques can be learned and, when practiced, improved. This article addresses the five biggest mistakes I have seen pre-meds make regarding interviews during my over 10+ years as a Harvard pre-med tutor and admissions consultant.