Research Basics: Should I Get Involved and How Do I Start?

research basics

The year is 1921. A medical student toils away at a dimly lit lab bench deep in the bowels of the University of Toronto. His intense concentration does not waver even as a bead of sweat begins to slip from his brow, splattering onto the chemical-stained surface below. Charles Best lets out a sigh of relief, unclenching the shoulders he had tightened while manipulating miniscule fragments of pancreatic tissue under the microscope.

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The Secondary Application: Bragging vs. Confidence

How can you brag about yourself without bragging about yourself?

We are taught from a  young age (most of us, anyway) not to brag. It is better, we may sometimes hear, to show confidence. Listener Rachel wrote in with a question about the secondary application: how does one confidently talk themselves up without coming across as a braggart? Lucky for Rachel, we have Daniel Schnall from our admissions staff on hand to help Mark Moubarek, Kylie Miller, Aline Sandouk, and Gabe Conley with some great advice about how to sell yourself on your application and also back it up.  Don’t want to look like a chump? Dan has your answer, Rachel.

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Hotel Influenza, Confirming Right-to-Try Problems, REM Sleep Revealed

We love when listeners get in touch, which is why Dave was glad to hear from Adil who, after listening to our discussion of the new national Right-To-Try legislation, sent us a paper he wrote on the subject the year before. It really helped clear some things up that we weren’t sure of. Like the fact that it doesn’t actually do anything to help patients get faster access to experimental drugs, has a kind of informed consent problem, allows patients to further conflate research with therapy, and more.

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5 Tips for Developing a USMLE Step 1 Study Plan

USMLE Step 1 study plan

Step 1 of the United States Medical Licensing Examination (or USMLE) covers all preclinical topics taught in medical school, from DNA replication to the details of disorders like ulcerative colitis and diabetes. Depending on your school’s curriculum, you may take this test anywhere between completion of your preclinical requirements and graduation, with the majority of schools offering a “dedicated” study period in which to review after wrapping up preclinical classes. No matter when you plan to take Step 1, however, one thing is clear: there is a lot to go over, and you probably do not feel like you have enough time to cover everything. Developing a reasonable study plan as you head into your dedicated study period can help reduce Step 1 preparation from an impossible task to one that seems difficult, yet doable. Studying for Step 1 will never be easy, but these five tips can make it more manageable:

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How would you manage this patient’s reaction?

A 32-year-old female presents with a headache and a rash on her trunk and extremities. She has had unprotected sex with multiple partners over the last two months, but denies any history of sexually transmitted infections. Examination reveals generalized non-tender lymphadenopathy, a diffuse macular rash on her chest and arms, and patchy hair loss. Venereal Disease Research Laboratory (VDRL) and fluorescent treponemal antibody-absorption (FTA-ABS) tests are both positive, and she is given a single dose of penicillin G benzathine intramuscularly. She returns within a few hours with a worsening rash (seen here), myalgia, and a fever.

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What is causing this woman’s recurring abdominal pain?

A 19-year-old female exchange student presents to the emergency department with severe abdominal pain and a swollen right knee. She has had recurrent episodes of abdominal pain for the past 5 years which last 2-3 days before resolving spontaneously. Previous investigations have all failed to identify a cause. She mentions that several family members back home in Turkey have similar symptoms. On examination, she has a temperature of 39.4°C and a heart rate of 125. Her abdomen is diffusely tender with rebound tenderness. A right knee effusion is present, and a raised, tender erythematous lesion on her left lower leg is noted. Laboratory testing reveals an elevated white cell count with a neutrophilic predominance, as well as elevated ESR, CRP, and SAA protein.

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