Physiology is different! If you’re in the midst of learning physiology, either in a traditional or systems course, you’ve noticed that it feels different from biochemistry and anatomy. There are several reasons. First, the stakes are high, as physiology is inextricably the basis for medicine; learning physiology has long-lasting, downstream consequences for understanding pathophysiology and clinical medicine. And physiology is the underpinning for Step 1, so learning it well in your courses is essential. Second, physiology cannot be memorized (and you’re good memorizers!). Physiology must be understood, and understanding can’t be rushed. You’re learning concepts and principles, rather than isolated facts, and you’re challenged by the hierarchy of concepts, interconnections, and recurring themes. Last and oh so important, you must make peace with graphs, equations, and calculations, since they are the language of physiology. Rather than concede up front that “I don’t do graphs,” it’s best to find a system for translating the mathematical side of physiology into something intuitive that speaks to you!